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  • Title: A case of systemic strongyloidiasis in an ex-coal miner with idiopathic colitis.
    Author: de Goede E, Martens M, Van Rooy S, VanMoerkerke I.
    Journal: Eur J Gastroenterol Hepatol; 1995 Aug; 7(8):807-9. PubMed ID: 7496874.
    Abstract:
    An ex-coal miner was diagnosed with an idiopathic sigmoiditis compatible with colitis ulcerosa. He was treated with corticosteroids because of his deteriorating clinical condition, but his condition continued to worsen. He revealed to have a systemic Strongyloides stercoralis hyperinfection and Strongyloides colitis. A short time after diagnosis he died from septic shock despite therapy with thiabendazole and antibiotics. S. stercoralis is an opportunistic infection that is not uncommon and has high mortality in hyperinfection. It is prevalent in (sub)tropical areas, and also in coal mines because of the specific microclimate. However, the parasite is difficult to detect because eosinophilia can appear normal in chronic infection. Several stool examinations, duodenal aspiration or biopsies are necessary for a high diagnostic sensitivity. Serological diagnosis is the most sensitive and specific but is not always available.
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