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  • Title: The in vitro migration inhibition of mononuclear cells in patients with colorectal carcinoma.
    Author: Kowalczyk D, Zembala M, Popiela T, Labza H.
    Journal: Arch Immunol Ther Exp (Warsz); 1978; 26(1-6):435-9. PubMed ID: 749793.
    Abstract:
    The response of peripheral blood mononuclear cells to PHA and PPD in migration inhibition test has been studied in patients with Duke's B-D colorectal carcinoma. It was found the response of patients cells to both stimulants was increased. This enhanced lymphokine release and/or production was closely connected with the tumor load. The implications of these findings to the regulatory mechanisms of the immune response in cancer patients are briefly discussed.
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