These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Combined therapy of mice bearing L1210 leukemia with adriamycin and mycobacteria.
    Author: Fiszer L, Mordarski M.
    Journal: Arch Immunol Ther Exp (Warsz); 1978; 26(1-6):873-9. PubMed ID: 749836.
    Abstract:
    Infection of CDF1 mice with non-toxic doses of different strains of mycobacteria had no influence on the growth rate of the L1210 leukemia. In combined therapy, pretreatment of mice with M. smegmatis did not show any significant effect on the antitumor activity of adriamycin when tested in mice inoculated iv with 10(3) leukemic cells. Moreover, for high doses of adriamycin (15, 20 mg/kg) combined with post-treatment with mycobacteria the shortened survival time was observed. In experiments in which mice were injected iv with 10(2) L1210 cells potentiation of antileukemic activity of adriamycin in infected animals was achieved.
    [Abstract] [Full Text] [Related] [New Search]