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  • Title: A new essential gene GCR4 located in the upstream region of GCR1.
    Author: Uemura H, Jigami Y.
    Journal: Yeast; 1995 Sep 15; 11(11):1093-101. PubMed ID: 7502585.
    Abstract:
    A new essential gene of Saccharomyces cerevisiae was found upstream of GCR1. Its cloning and sequencing predict a 280 amino acid protein (32,577 Da). The predicted protein is fairly hydrophobic, and a search of the database did not identify any homologous proteins. A LEU2 disruption at codon 104 was lethal, but disruption at codon 221 showed a temperature-sensitive conditional growth phenotype. Abnormalities were observed in some glycolytic enzyme levels.
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