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  • Title: Influence of 2-chloro-2'-deoxyadenosine alone and in combination with cyclophosphamide or methotrexate on murine leukemia L1210.
    Author: Góra-Tybor J, Robak T, Warzocha K, Grieb P.
    Journal: Arch Immunol Ther Exp (Warsz); 1994; 42(1):39-42. PubMed ID: 7503633.
    Abstract:
    The influence of 2-CdA administrated alone and in combination with CY or MTX on the survival time of mice bearing L1210 leukemia was investigated. 2-CdA treated mice lived longer than control animals. Survival times of mice receiving combined therapy of 2-CdA and CY were significantly prolonged as compared with mice treated with these agents separately. Survival times of mice treated with 2-CdA and MTX were not significantly prolonged, compared with animals receiving 2-CdA alone.
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