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  • Title: Clinical review of risperidone.
    Author: Chouinard G, Arnott W.
    Journal: Can J Psychiatry; 1993 Sep; 38 Suppl 3():S89-95. PubMed ID: 7504574.
    Abstract:
    Phase II clinical trials with risperidone have proven it to have a potent antipsychotic effect, improving both positive and negative symptoms of schizophrenia. It was found to have a low potential for inducing extrapyramidal symptoms and has been shown to have a possible antidyskinetic effect without increasing parkinsonism. Risperidone has a rapid onset of action and a favourable side-effect profile. One-year data on risperidone suggest that its therapeutic action in patients with chronic schizophrenia can be maintained without the significant neurological side-effects associated with the use of standard neuroleptics.
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