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  • Title: Human red blood cell membrane adenylate cyclase in sickle-cell disease.
    Author: Delaunay J, Piau JP, Girot R, Fischer S, Tortolero M, Schapira G.
    Journal: Isr J Med Sci; 1978 Nov; 14(11):1170-2. PubMed ID: 750545.
    Abstract:
    The basal and the NaF-stimulated activities of human red blood cell membrane adenylate cyclase were found to be 5.3 +/- 0.8 (SE) and 219 +/- 76 (SE) pmol . mg-1 . min-1, respectively. Both activities were increased in nine patients with homozygous sickle-cell disease. There was no apparent correlation between this increase and the increase in the reticulocyte count.
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