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  • Title: In vivo effect of chlorophyllin on gamma-ray-induced sister chromatid exchange in murine bone marrow cells.
    Author: Morales-Ramírez P, García-Rodríguez MC.
    Journal: Mutat Res; 1994 Mar; 320(4):329-34. PubMed ID: 7508558.
    Abstract:
    The aim of the present work is to determine the radioprotective capacity of chlorophyllin, by measuring the reduction of gamma-ray-induced sister-chromatid exchange (SCE) in murine bone marrow cells in vivo. The results obtained in two separate experiments, using 10, 50 and 100 micrograms of chlorophyllin per g of body weight (bw), indicate that chlorophyllin per se did not have any effect on the SCE frequency and that the dose of 100 micrograms/g bw protects 100% against the induction of SCE by 1.0 Gy of gamma-rays; 50 micrograms/g bw protects less than 50% and 10 micrograms/g bw affords no protection.
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