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  • Title: In vivo cytogenetic analyses of the carbamate pesticides Dithane M-45 and Baygon in mice.
    Author: Vasudev V, Krishnamurthy NB.
    Journal: Mutat Res; 1994 Mar; 323(3):133-5. PubMed ID: 7509028.
    Abstract:
    Two carbamate pesticides, Dithane M-45 and Baygon, were analysed for their cytogenetic effects using meiotic chromosome analysis and the micronucleus test in Swiss albino male mice. The three sub-lethal doses of 1687.5, 3375 and 5962.5 mg/kg bw of Dithane M-45 and 1250, 2500 and 3750 mg/kg bw of Baygon were employed in all the experiments. The results demonstrate that neither Dithane M-45 nor Baygon could induce a significant (P > 0.05) increase in the number of chromosomal aberrations in the germ cells or in the percentage of micronuclei in erythrocytes.
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