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  • Title: Synthesis and pharmacological properties of 1,3 and 5-substituted 2-pyrrolidinones.
    Author: Gorczyca M, Malawska B, Chojnacka-Wójcik E.
    Journal: Pol J Pharmacol Pharm; 1978; 30(5):675-83. PubMed ID: 751008.
    Abstract:
    We described synthesis of 1-aryl-3 and 5-substituted 2-pyrrolidinones (2a--5a and 3b--4b). Pharmacological studies revealed that compounds 3b, 4a and 4b have analgetic and antiinflammatory properties. None of the compounds posesses neuroleptic or anticonvulsant properties.
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