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  • Title: Dermal toxicity of hexachlorocyclohexane and pirimiphos-methyl in female rats.
    Author: Raizada RB, Srivastava MK, Kaushal RA, Singh RP, Gupta KP, Dikshith TS.
    Journal: Vet Hum Toxicol; 1994 Apr; 36(2):128-30. PubMed ID: 7515208.
    Abstract:
    Technical hexachlorocyclohexane (100 mg/kg/d) and pirimiphosmethyl EC 50 (250 mg/kg/d) given individually and in combination to female rats for 7, 15 or 30 d by skin application caused poisoning, pathomorphological changes in vital organs, and significant enzymatic changes in liver and serum. The changes produced by the 2 compounds in combination did not suggest potentiation at the tested dose levels.
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