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  • Title: A high frequency of induction of chromosome aberrations in the bone marrow cells of LEC strain rats by X-irradiation.
    Author: Okui T, Hayashi M, Endoh D, Sato F, Kasai N, Watanabe T, Namioka S.
    Journal: Mutat Res; 1994 Aug; 324(4):165-9. PubMed ID: 7519741.
    Abstract:
    LEC strain rats, which have been known to develop hereditarily spontaneous fulminant hepatitis 4 to 5 months after birth, are highly sensitive to whole-body X-irradiation when compared to WKAH strain rats. The present results showed that the frequencies of all types of chromosome aberrations induced by X-irradiation in the bone marrow cells of LEC rats were approximately 2- to 3-fold higher than those of WKAH rats, though no significant difference was observed in the frequency of spontaneous chromosome aberrations between LEC and WKAH rats.
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