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  • Title: Efficacy of treatment and recurrence rate of leukocytospermia in infertile men with prostatitis.
    Author: Branigan EF, Muller CH.
    Journal: Fertil Steril; 1994 Sep; 62(3):580-4. PubMed ID: 7520396.
    Abstract:
    OBJECTIVE: To identify men with leukocytospermia and prostatitis in an infertility practice and evaluate the effect of various treatments and recurrence rates after treatment. DESIGN: A prospective randomized trial of men with leukocytospermia. SETTING: Academic tertiary infertility clinic. PATIENTS: One hundred two men with leukocytosperimia identified on smear of semen using Bryan-Leishman stain and in expressed prostatic secretion. INTERVENTIONS: Treatment groups were no treatment group; antibiotic treatment alone group; frequent ejaculation alone group; and antibiotic treatment with frequent ejaculation group. MAIN OUTCOME MEASURE: Resolution of leukocytospermia on semen smear. RESULTS: Significant resolution of leukocytospermia occurred in all treatment groups at 1 month compared with no treatment. The resolution was sustained at 2 and 3 months only in those who took antibiotics and frequently ejaculated. CONCLUSIONS: Antibiotic treatment, frequent ejaculation, and antibiotic treatment with frequent ejaculation effectively treat leukocytospermia immediately after the treatment phase. However, only antibiotic treatment coupled with frequent ejaculation is effective 3 months after treatment.
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