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Title: Isolation and characterization of the major equilibrium product of FK-520. Author: Gailliot FP, Natishan TK, Ballard JM, Reamer RA, Kuczynski D, Mcmanemin GJ, Egan RS, Buckland BC. Journal: J Antibiot (Tokyo); 1994 Jul; 47(7):806-11. PubMed ID: 7520900. Abstract: The existence of an isomeric form in equilibrium with the major component of FK-520 in polar solutions has been demonstrated. This minor component has been isolated in high yield and purity by a novel crystallization strategy and preparative HPLC. The equilibrium product was characterized by NMR and MS.[Abstract] [Full Text] [Related] [New Search]