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  • Title: [Examination in clinical course of HCV in interferon treatment].
    Author: Kumada H.
    Journal: Nihon Rinsho; 1994 Jul; 52(7):1832-5. PubMed ID: 7521426.
    Abstract:
    We treated 812 patients who had chronic hepatitis C with interferon (IFN) and studied the effects of interferon. We defined complete response as normalization of amino-transferase more than 6 months after termination of IFN. Complete response by means of IFN therapy is dependent to some factors, that is HCV-genotype, quantity of HCV-RNA, histology. Cases of HCV genotype III or IV, CH2A, less than 10(5) copy/ml of HCV-RNA are effective in treatment of IFN. On the other hand, cases of HCV genotype II, CH2B, more than 10(6) copy/ml of HCV-RNA are effective in treatment of IFN.
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