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  • Title: [The value of Sm-153-EDTMP for treatment of metastatic bone pain and improving quality of life].
    Author: Jiang CY, Zhu BL, Zhang YJ.
    Journal: Zhonghua Zhong Liu Za Zhi; 1994 Mar; 16(2):118-21. PubMed ID: 7523052.
    Abstract:
    Sm-153-EDTMP (ethylenediaminetetramethylene phosphonic acid), a beta-particle and gamma-emitting radionuclide, was used for pain control of bone metastasis. Fourty patients with bone metastasis were administrated a single intravenous injection of 29.6 MBq/kg (0.8mCi/kg), and 7 of them received more than one injection. No obvious side effect was observed. The skeletal images obtained with Sm-153-EDTMP were similar to that of Tc-99m-MDP SPECT images. Follow up study (at least 30 days) revealed bone pain relief and improved quality of life in 82.5% of the treated patients.
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