These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Involvement of the brain type of ryanodine receptor in T-cell proliferation.
    Author: Hakamata Y, Nishimura S, Nakai J, Nakashima Y, Kita T, Imoto K.
    Journal: FEBS Lett; 1994 Sep 26; 352(2):206-10. PubMed ID: 7523185.
    Abstract:
    Cloning and sequence analysis of cDNA showed that the brain type of ryanodine receptor (RYR) is expressed in human Jurkat T-lymphocyte cells. Fura-2 measurements revealed that the RYR in T-cells functions as a ryanodine-sensitive, caffeine-insensitive Ca2+ release channel. Furthermore, ryanodine stimulated proliferation and altered the growth pattern of cultured human T-cells when added together with FK506.
    [Abstract] [Full Text] [Related] [New Search]