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  • Title: Serum soluble E-selectin levels in Kawasaki disease.
    Author: Kim DS, Lee KY.
    Journal: Scand J Rheumatol; 1994; 23(5):283-6. PubMed ID: 7526448.
    Abstract:
    Serum sE-selectin levels in KD were tested. In the KD patients' sera during the acute phase, the levels of circulating sE-selectin were markedly elevated (27.5 +/- 10.9 ng/ml) compared to 3.1 +/- 1.0 ng/ml in the control subjects (p < 0.0001). The serum sE-selectin levels remained significantly elevated in the subacute phase (16.2 +/- 7.3 ng/ml; p < 0.005). The acute phase sE-selectin levels and TNF-alpha correlated well in a linear pattern (r2 = 0.64, p < 0.01). Also the acute phase sE-selectin levels and IL-6 were well correlated (r2 = 0.54, p < 0.05). The elevated serum sE-selectin levels in patients with KD provides additional evidence for the relationship between acute vasculitis and serum sE-selectin.
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