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  • Title: Nephrotoxicity of immunosuppressive drugs.
    Author: Bennett WM, Burdmann EA, Andoh TF, Houghton DC, Lindsley J, Elzinga LW.
    Journal: Nephrol Dial Transplant; 1994; 9 Suppl 4():141-5. PubMed ID: 7528363.
    Abstract:
    Acute and chronic nephrotoxicity frequently limits the therapeutic benefits of immunosuppressive therapy for transplant and autoimmune indications. The clinical aspects, pathophysiology, and relevant pharmacology of current and future immunosuppressive drugs are reviewed in this paper. Insights gained from experimental models of chronic nephrotoxicity associated with tubulointerstitial fibrosis are presented.
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