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  • Title: Cell kinetic investigations in craniopharyngioma: preliminary results and considerations.
    Author: Broggi G, Franzini A, Cajola L, Pluchino F.
    Journal: Pediatr Neurosurg; 1994; 21 Suppl 1():21-3. PubMed ID: 7530989.
    Abstract:
    In vitro determination of 3H-thymidine labeling index (LI%) was carried out in craniopharyngiomas from 16 patients submitted to repeated surgical procedures. This study showed a poor correlation between LI% values and prognosis, but allowed to detect a high LI% variation in the same tumor investigated in serial different times. The spatial distribution of S-phase proliferative cells in squamous epithelium of cystic components suggests a rationale for intracavitary treatment of cystic and mixed craniopharyngioma and may help explain its success.
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