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  • Title: Monoclonal IgM reactive with several gangliosides in a chronic relapsing polyneuropathy.
    Author: Brindel I, Preud'homme JL, Vallat JM, Vincent D, Vasquez JL, Jauberteau MO.
    Journal: Neurosci Lett; 1994 Nov 07; 181(1-2):103-6. PubMed ID: 7534889.
    Abstract:
    A possibly pathogenic serum monoclonal IgM lambda from a patient with chronic relapsing polyneuropathy was shown to react with the disialosyl-lactosyl residue (NeuAc alpha 2-8NeuAc alpha 2-3) -Gal beta 1-4Glc expressed by GD1b, GT1b, GQ1b, GD2 and GD3. A part of this epitope in terminal position in GM3, GD1a and LM1 was also recognized by the IgM lambda.
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