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  • Title: [Malignant transformation of odontogenic cysts].
    Author: Timoşca GC, Cotuţiu C, Gavriliţà L.
    Journal: Rev Stomatol Chir Maxillofac; 1995; 96(2):88-95. PubMed ID: 7537384.
    Abstract:
    Five out of 4,172 operated maxillary cysts (3 developed within the maxillary and 2 in the mandible) presented a malignant change of epithelium. In all these 5 cases histology demonstrated a transition from normal to cancerous epithelium. The overall percentage of malignant change was of 0.12%, with 0.077% for non-keratinized epithelium lining odontogenic cysts (3 cases) and 0.65%, that is 8 times higher, for keratinized ones (2 cases). Keratinization of cystic epithelium and chronic inflammatory lesions were the main risk factors.
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