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  • Title: [A case of mitochondrial myopathy with progressive chronic ophthalmoplegia (author's transl)].
    Author: Gallai V, Rossi A, Cianchetti A, Morocutti C, Vaccario ML.
    Journal: Riv Patol Nerv Ment; 1977; 98(6):333-46. PubMed ID: 754250.
    Abstract:
    Clinical, electromyographic, histochemical and ultrastructural features are described in a case of Chronic Progressive Ophthalmoplegia. The neurogenic-myogenic aspects of the diseases are discussed bearing in mind both electromyographic and histological findings ("red ragged fibres" etc.). Mitochondrial paracrystalline inclusions were found at the level of the ocular muscles as well as in the skeletal muscles. These inclusione suggest that Ocular Myopathy is a form of systemic myopathy secondary to mitochondrial abnormalities.
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