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  • Title: Microwave hyperthermia in benign prostatic hypertrophy: a controlled clinical trial.
    Author: Venn SN, Montgomery BS, Sheppard SA, Hughes SW, Beard RC, Bultitiude MI, Lloyd-Davies RW, Tiptaft RC.
    Journal: Br J Urol; 1995 Jul; 76(1):73-6. PubMed ID: 7544207.
    Abstract:
    OBJECTIVE: To compare the effects of microwave hyperthermia in benign prostatic hypertrophy (BPH) to sham treatment. PATIENTS AND METHODS: The trial included 96 patients with proven symptomatic bladder outflow obstruction (BOO) caused by BPH. Patients underwent a full subjective and objective assessment (including urodynamics) before inclusion and again 3 and 6 months later. They were randomly assigned to receive 1 h of microwave hyperthermia or a sham treatment. Of the 96 patients, 93 were assessed at 3 months and 62 at 6 months after treatment. RESULTS: There was no statistically significant difference in the objective measures of BOO between the treated and control groups of patients. There was an improvement of approximately 40% in all the subjective measures, but there was no significant difference between the treated and control groups. CONCLUSION: Microwave hyperthermia, within the parameters defined in this trial, resulted in no significant difference from sham treatment in subjective or objective outcome.
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