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  • Title: Transitional cell carcinoma of the upper urinary tract: staging by MRI.
    Author: Weeks SM, Brown ED, Brown JJ, Adamis MK, Eisenberg LB, Semelka RC.
    Journal: Abdom Imaging; 1995; 20(4):365-7. PubMed ID: 7549745.
    Abstract:
    BACKGROUND: This study evaluates the ability of MRI to stage transitional cell carcinoma of the upper urinary tract. METHODS: Nine patients who had transitional cell carcinoma of the upper urinary tract detected by other imaging modalities underwent MRI examination at 1.5 T. Imaging included pre- and postgadolinium-DTPA T1-weighted images (9 patients) pre- and postgadolinium chelate T1-weighted fat-suppressed spin echo (7 patients). Postcontrast images were acquired prior to the presence of gadolinium within the collecting system (< 2 min postcontrast), intermediate (2.5-8 min), and late (> 10 min) postcontrast. Images were prospectively interpreted and lesion staging was determined. Correlation with histopathology was obtained in all cases. RESULTS: Transitional cell cancers were demonstrated in 9/9 patients, and tumors ranged in size from 2 to 8 cm (mean = 3.8 cm) in one dimension. Correct tumor staging was performed in 8/9 patients. The staging error in one case occurred because direct tumor extension into the renal parenchyma was not detected. CONCLUSIONS: The results of this preliminary study show that MRI stages transitional cell cancers relatively well; however, MRI is not able to detect superficial invasion of renal parenchyma.
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