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  • Title: Changes of beta-glucuronidase activity in peripheral blood lymphocytes in rats exposed to a mixture of nitrogen oxides and chlorine.
    Author: Starek A, Moszczyński P.
    Journal: Pol J Pharmacol Pharm; 1978; 30(6):819-24. PubMed ID: 755246.
    Abstract:
    The activity of beta-glucuronidase (BG) was tested cytochemically in the lymphocytes of peripheral blood of rats exposed to a mixture of nitrogen oxides (1.22 mg/m3) and chlorine (1.02 mg/m3) for 12 weeks. The number of lymphocytes was reduced, the activity of BG was depressed and the enzyme was shifted from the lysosomes to the cytoplasm of these cells. A relation between the changes in the lymphocytes at the subcellular level and the immunological responses of the organism are discussed.
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