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  • Title: Concurrent hypoadrenocorticism and hypoalbuminemia in dogs: a retrospective study.
    Author: Langlais-Burgess L, Lumsden JH, Mackin A.
    Journal: J Am Anim Hosp Assoc; 1995; 31(4):307-11. PubMed ID: 7552662.
    Abstract:
    A retrospective study was undertaken to determine the prevalence of hypoalbuminemia in dogs with hypoadrenocorticism. During a 94-month interval, 17 of 44 dogs (38.6%) with hypoadrenocorticism were found to have hypoalbuminemia. When compared to all dogs with hypoalbuminemia (9.8%) observed in the hospital population during this same interval, there appeared to be a significant association between canine adrenocortical insufficiency and hypoalbuminemia. The pathogenesis of the hypoalbuminemia in this study is speculative; possible mechanisms include gastrointestinal blood loss, protein-losing enteropathy, malassimilation, or decreased albumin synthesis. Renal protein loss was not supported by routine urinalysis findings.
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