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  • Title: Inhibition of cysteine proteinases by Carica papaya cystatin produced in Escherichia coli.
    Author: Song I, Taylor M, Baker K, Bateman RC.
    Journal: Gene; 1995 Sep 11; 162(2):221-4. PubMed ID: 7557432.
    Abstract:
    A papaya cystatin (Cst)-encoding cDNA clone was isolated from a papaya leaf cDNA library and the active protein produced in Escherichia coli. The amino-acid sequence reveals a protein of 11,262 Da with over 40% identity to other published plant Cst. Unique features of the papaya Cst include a single Cys residue, variation in the papain-binding region, and the first reported inhibition of papaya proteinase IV by a Cst.
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