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Title: Structural organization and mapping of the human TCF11 gene. Author: Luna L, Skammelsrud N, Johnsen O, Abel KJ, Weber BL, Prydz H, Kolstø AB. Journal: Genomics; 1995 May 20; 27(2):237-44. PubMed ID: 7557987. Abstract: We recently cloned human cDNA representing several mRNA isoforms of human TCF11, a transcription factor of the basic-region, leucine-zipper (bZIP) family located on chromosome 17q22 as well as a genomic clone of this gene. We have now determined the complete genomic organization of the TCF11 gene, which consists of 9 exons distributed over 15 kb of genomic DNA. Pulsed-field gel electrophoresis was used to construct a physical map around TCF11, to characterize a 450-kb YAC clone that contains the gene, and to link TCF11 physically to BTR, a marker on chromosome 17.[Abstract] [Full Text] [Related] [New Search]