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  • Title: [Cytotoxicity of aspidospermane indole alkaloids with a modified tryptamine chain].
    Author: Lewin G.
    Journal: J Nat Prod; 1995 Jul; 58(7):1089-91. PubMed ID: 7561901.
    Abstract:
    Eight synthetic indole alkaloids with the aspidospermane structure have ben evaluated for cytotoxicity in the L-1210 cell culture test system. Two of them (compounds 9 and 5), bearing a modified tryptamine chain, were significantly active (IC50 values of 0.7 and 3.1 microM, respectively).
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