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  • Title: Activated sialidase activity in transformed lymphocytes by Epstein-Barr (EB) virus of sialidosis type I (cherry-red spot-myoclonus syndrome).
    Author: Yamamoto M, Yamauchi T, Yamamoto K, Kobayashi T.
    Journal: J Neurol Sci; 1995 Jul; 131(1):105-7. PubMed ID: 7561940.
    Abstract:
    We report a new Japanese family of sialidosis type I. The sialidase activity was deficient in the lymphocytes of 2 patients (6.8% (sister) and 12.5% (brother) of control mean). However, surprisingly, using the transformed lymphocytes by EB virus, this activity was activated to 51.7% (sister) and 49.5% (brother) of control mean, respectively. Although the mechanism for this activation was not known, we discussed the possible mechanisms for this phenomenon.
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