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  • Title: Homodimers of chromosomal proteins HMG-14 and HMG-17 in nucleosome cores.
    Author: Postnikov YV, Trieschmann L, Rickers A, Bustin M.
    Journal: J Mol Biol; 1995 Sep 29; 252(4):423-32. PubMed ID: 7563062.
    Abstract:
    In this work, we report that nucleosome core particles interact with an equimolar mixture of the chromosomal proteins HMG-14 and HMG-17 to form, exclusively, complexes containing two molecules of either HMG-14 or HMG-17 (homodimers). Analysis of the binding of various mixtures of wild-type proteins and their deletion mutants indicates that homodimer formation is not dependent on contacts between the nucleosome-bound HMG-14/-17 proteins themselves. We suggest that HMG-14/-17 proteins in nucleosomes cross-talk by inducing specific allosteric transitions in the chromatin subunit.
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