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  • Title: [Effects of medical vagotomy and sympathectomy on gastric mucosal prostaglandins in water immersion restrain rats].
    Author: Tanaka M.
    Journal: Nihon Shokakibyo Gakkai Zasshi; 1995 Aug; 92(8):1133-42. PubMed ID: 7563920.
    Abstract:
    Ulcer index (UI), gastric submucosal blood flow (SMBF), gastric fundic mucosal content of 5 prostaglandins (PGE2, TXB2, PGF2 alpha, PGD2, 6-keto-PGF1 alpha) were measured in water immersion restrain rats under medical vagotomy (MV) or medical sympathectomy (MSp). UI decreased under MV and MSp with 6 hours stress. SMBF decreased less under MV and MSp than control rats. PGE2 of control rats decreased under stress, but increased under MV and MSp. It is resulted that MV and MSp effect PGE2 to increase, inhibition of SMBF decreasing because of increasing PGE2 were recognised and there for stress ulcer were inhibited.
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