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  • Title: Effects of long-term zearalenone administration on spermatogenesis and serum luteinizing hormone, follicle-stimulating hormone, and prolactin values in male rats.
    Author: Milano GD, Becú-Villalobos D, Tapia MO.
    Journal: Am J Vet Res; 1995 Jul; 56(7):954-8. PubMed ID: 7574167.
    Abstract:
    Body and testis weights, serum luteinizing hormone, follicle-stimulating hormone, and prolactin values and volume fractions of Sertoli cells, spermatogonia, early and late primary spermatocytes, and round and long spermatids were evaluated in 70-day-old male rates treated orally with 20 mg of zearalenone/kg of body weight daily for 5 weeks. Significant (P < 0.05) increase in serum prolactin concentration was consistently observed during the 5 weeks of treatment with zearalenone. Significant changes were not observed in any of the other variables evaluated.
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