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  • Title: [Experience in intra-hepatic-arterial chemotherapy and hepatic resection for metastatic colorectal cancer].
    Author: Shimada H, Ozaki M, Ariga T, Ooshima I, Maruyama T, Kinoshita H, Takeda A, Yoshimura S, Shouko T.
    Journal: Gan To Kagaku Ryoho; 1995 Sep; 22(11):1570-2. PubMed ID: 7574762.
    Abstract:
    Out of 213 consecutive cases of colorectal cancer patients, 39 patients had liver metastasis (31 synchronous metastases and 8 metachronous metastases). One-and 3-year survivals of these patients with liver metastases were 46.5% and 30.1%, respectively. Twenty-four patients who were treated with intra-hepatic-arterial chemotherapy had better survival rates of 54.7% at 1 year, and 36.5% at 3 years than non-treated patients. Fifteen patients who underwent curative hepatic resection had better survival rates of 83.1% at 1 year, and 48.5% at 3 years than non-resected patients. Thirteen patients who underwent curative hepatic resection followed by intra-hepatic-arterial chemotherapy had good survival rates of 80.8% at 1 year, and 53.9% at 3 years. Seven patients who had multiple metastases to both lobes, were treated with intra-hepatic-arterial chemotherapy. These patients had a better survival rate of 22.9% at 1 year than non-treated patients.
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