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  • Title: Optimal size matching in single lung transplantation.
    Author: Park SJ, Houck J, Pifarre R, Sullivan H, Garrity E, Kim SY, Zbilut J, Montoya A.
    Journal: J Heart Lung Transplant; 1995; 14(4):671-5. PubMed ID: 7578174.
    Abstract:
    BACKGROUND: Single lung transplantation for patients with end-stage obstructive lung disease has been highly effective in providing symptomatic relief, and it has been performed at a much increased frequency since 1983. However, there still lacks a convincing study showing the effect of size match and other preoperative variables in predicting functional outcome of patients after transplantation. METHODS: We evaluated 23 single lung transplantations performed for obstructive lung disease over a 34-month period. Multiple physiologic variables and size match criteria were evaluated for their contribution in determining the postoperative forced expiratory volume in 1 second at 3 months after transplantation. RESULTS: The size match ratio that was based on inframammary chest wall circumference was the most useful criterion to adopt, and the optimal donor/recipient size match ratio was 0.89. Furthermore, forced expiratory volume in 1 second at 3 months after transplantation could be predicted with a simple mathematical model that was based on the size match ratio and the recipient's calculated vital capacity of the transplanted hemithorax. CONCLUSIONS: This model could be applied in a clinical setting to maximize functional outcome of the recipients undergoing single lung transplantation.
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