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  • Title: The effects of propofol on laryngeal reactivity and the haemodynamic response to laryngeal mask insertion.
    Author: Acalovschi I, Miclescu A, Bugov L.
    Journal: Eur J Anaesthesiol; 1995 Jul; 12(4):351-6. PubMed ID: 7588663.
    Abstract:
    The ease of the insertion of laryngeal mask and the haemodynamic response were assessed 2 min after induction of anaesthesia with either propofol 2.5 mg kg-1 or thiopentone 4.0 mg kg-1 in 38 ASA I premedicated patients. The inserting conditions scored as excellent, good, poor and unable to insert were significantly better with propofol than with thiopentone (P < 0.001). Insertion of the laryngeal mask was followed by a transient but significant increase in both systolic (P < 0.05) and diastolic (P < 0.01) arterial pressure in the thiopentone group; there was no comparable response in the propofol group. The heart rate varied little from baseline in both groups.
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