These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: A comparison of resting images from two myocardial perfusion tracers.
    Author: Anagnostopoulos C, Laney R, Pennell D, Proukakis H, Underwood R.
    Journal: Eur J Nucl Med; 1995 Sep; 22(9):1029-34. PubMed ID: 7588940.
    Abstract:
    We have compared stress-redistribution and delayed rest thallium-201 with rest technetium-99m methoxyisobutylisonitrile (MIBI) tomograms in order to compare the tracers for the assessment of myocardial viability and to validate a rapid protocol combining the two tracers. We studied 30 consecutive patients with known or suspected coronary artery disease [group 1: 16 with normal left ventricular function, mean left ventricular ejection fraction (LVEF) 55%, SD 6%; group 2: 14 with abnormal function, mean LVEF 28%, SD 8%]. 201Tl was injected during infusion of adenosine followed by acquisition of conventional stress and redistribution tomograms. On a separate day, 201Tl was injected at rest with imaging 4 h later. 99mTc-MIBI was then given at rest and imaging was performed. Three images were compared: redistribution 201Tl, rest 201Tl, and rest 99mTc-MIBI. Tracer activity was classified visually and quantitatively in nine segments and segments with > 50% activity were defined as containing clinically significant viable myocardium. Mean (+/- SD) global tracer uptake as a percentage of maximum was similar in group 1 (rest 201Tl 69% +/- 12%, redistribution 201Tl 69% +/- 15%, rest 99mTc-MIBI 70% +/- 13%, ANOVA P > 0.05), but in group 2 mean tracer uptake was significantly greater in the rest 201Tl images (59% +/- 16%) than in redistribution 201Tl images (53% +/- 17%) or rest 99mTc-MIBI images (53% +/- 19%) (ANOVA P = 0.02).(ABSTRACT TRUNCATED AT 250 WORDS)
    [Abstract] [Full Text] [Related] [New Search]