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  • Title: Effect of prolonged exercise on neutrophil myeloperoxidase secretion.
    Author: Bury TB, Pirnay F.
    Journal: Int J Sports Med; 1995 Aug; 16(6):410-2. PubMed ID: 7591394.
    Abstract:
    This study was designed to compare the effects of three prolonged exercises on plasma myeloperoxidase concentrations, used as marker of neutrophil degranulation. Seven healthy subjects underwent three effort trials (45% VO2max during 4 h, 60% VO2max during 3 h, 75% VO2max during 2 h) at one-month intervals. Blood samples were collected before, during and after exercise. Myeloperoxidase levels were measured by radioimmunoassay. We observed a significant increase in myeloperoxidase concentration (+85%) at the end of our three prolonged exercises (p < 0.05). This myeloperoxidase increase was not correlated with the modification of neutrophil count, suggesting that neutrophil degranulation is independent of their mobilisation.
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