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  • Title: [Angio-immunoblastic lymphadenopathy (author's transl)].
    Author: Hug J, Gudat F, Speck B, Weber W, Wey W.
    Journal: HNO; 1979 Jan; 27(1):25-8. PubMed ID: 759411.
    Abstract:
    The general clinical and pathological findings of angio-immunoblastic lymphadenopathy are reviewed and illustrated by a case-report with involvement of the tonsils. Our patient showed all the characteristic signs of this disease, including fever, pruritus, rash, generalized lymphadenopathy and hepatosplenomegaly. Histologically the wellknown triad of arborizing postcapillary vessels, proliferation of immunoblasts and plasma-cells, as well as deposition of PAS-positive interstitial material was found. Laboratory findings included a polyclonal hyperglobulinemia and a hemolytic anemia. Treatment consisted of corticosteroids and supportive medications. The prognosis is generally poor, with a median survival of 13 months. At present, the cause is unknown.
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