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  • Title: Raised alpha-fetoprotein levels in amniotic fluid and maternal serum associated with distension of the fetal bladder caused by absence of urethra.
    Author: Nevin NC, Ritchie A, McKeown F, Roberts G.
    Journal: J Med Genet; 1978 Feb; 15(1):61-3. PubMed ID: 75973.
    Abstract:
    Raised alpha-fetoprotein concentrations were found at 29 and 30 weeks' gestation in the amniotic fluid and maternal serum of a woman who presented in her seventh pregnancy with apparent polyhydramnios. The fetus had multiple abnormalities including gross distension of the bladder resulting from absence of the urethra, intestinal artresia, and a congenital heart defect.
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