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  • Title: A regulatory locus for mouse beta-glucuronidase induction, Gur, controls messenger RNA activity.
    Author: Paigen K, Labarca C, Watson G.
    Journal: Science; 1979 Feb 09; 203(4380):554-6. PubMed ID: 760204.
    Abstract:
    A regulatory locus in a higher organism has been shown to control a specific messenger RNA activity. The Gur locus in mice regulates the production of kidney beta-glucuronidase messenger RNA activity after induction of the beta-glucuronidase structural gene, Gus, by testosterone. beta-Glucuronidase messenger RNA was assayed by its ability to direct the synthesis of catalytically active murine beta-glucuronidase in Xenopus oocytes.
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