These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Effect of trimethoprim-sulphamethoxazole in Langerhans' cell histiocytosis: preliminary observations.
    Author: Tzortzatou-Stathopoulou F, Xaidara A, Mikraki V, Moschovi M, Arvanitis D, Ageloyianni P, Prodromou P.
    Journal: Med Pediatr Oncol; 1995 Aug; 25(2):74-8. PubMed ID: 7603404.
    Abstract:
    Twenty-three children with Langerhans' cell histiocytosis (LCH) have been treated with trimethoprim-sulphamethoxazole (T-S) in a 4-year period. The children are classified in two main groups according to the extent of their disease. Group A includes 16 children with single system disease and group B, seven children with multisystem disease. All patients were treated for 4 weeks to 3 months. The results of treatment are evaluated in terms of response in individual organs involved. All children with single system disease had a good response to the drug. Children with multisystem disease had a good response to some organs but a poorer outcome for the lungs and for the blood. These patients did not respond even to conventional chemotherapy.
    [Abstract] [Full Text] [Related] [New Search]