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  • Title: [A mutable X(Z)-chromosome isolated from a natural population of Drosophila melanogaster].
    Author: Iurchenko NN, Zakharov IK.
    Journal: Genetika; 1995 Mar; 31(3):422-6. PubMed ID: 7607432.
    Abstract:
    In 1986, a mutable XZ-chromosome, in which mutation at genes yellow, white, and singed were recorded, was isolated from a natural population of Drosophila melanogaster from Zaporozh'e. Visible mutations in the region garnet-forked were also detected. Mutations appeared at a rate of about 10(-4) and were probably postmeiotic. Cytological analysis showed that two types of inversions occurred independently in XZ-chromosome. Specific features of this chromosome are hypermutability of the white locus (the mutation rate was approximately 10(-3) and a hot spot for chromosomal rearrangements in the terminal segment of the X-chromosome.
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