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  • Title: [DNA level in cell nuclei of squamous cell carcinoma of the tongue and mouth floor mucosa as an indicator of the biological behavior of the tumor].
    Author: Rozanov IM, Bychkova NV, Korobkin VA, Chepik OF, Pozharisskiĭ KM.
    Journal: Vopr Onkol; 1994; 40(7-12):294-8. PubMed ID: 7610623.
    Abstract:
    DNA was assayed in cell nuclei of squamous-cell carcinoma of the tongue (35 cases) and mucosa of the oral cavity fundus (15) using flow cytometry. The measurements were made versus size of tumor, cell differentiation stage and presence of metastasis to regional lymph nodes. Aneuploidy incidence was found to be in direct correlation with tumor size, low cell differentiation and ability to disseminate.
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