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Title: Pentylenetetrazole kindling impairs long-term memory in rats. Author: Genkova-Papazova MG, Lazarova-Bakarova MB. Journal: Eur Neuropsychopharmacol; 1995 Mar; 5(1):53-6. PubMed ID: 7613103. Abstract: The effect of pentylenetetrazole (PTZ) kindling on learning and retention in active (shuttle-box) and passive (step-down) avoidance was studied in rats. PTZ kindling did not impair learning and significantly disturbed long-term memory estimated from retention tests, i.e. PTZ kindling induced a retrograde amnesia in the active and passive avoidance situations. The present results support the view that memory deficit is an integral part of epilepsy.[Abstract] [Full Text] [Related] [New Search]