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  • Title: Comparison of two rapid streptococcal antigen detection assays with culture for diagnosis of streptococcal pharyngitis.
    Author: Heiter BJ, Bourbeau PP.
    Journal: J Clin Microbiol; 1995 May; 33(5):1408-10. PubMed ID: 7615768.
    Abstract:
    In this study, 801 pharyngeal specimens were cultured for group A streptococci and tested with the Biostar Strep A Optical Immunoassay (Strep A OIA). The respective sensitivities and specificities were as follows: culture, 97.1 and 100%; Strep A OIA, 91.5 and 94.8%. Of the 801 specimens, 597 were also tested with the Abbott TestPack Strep A Assay (TP-ST). For those specimens tested by all three methods, the respective sensitivities and specificities were as follows: culture, 98.1 and 100%; Strep A OIA, 92.3 and 95.4%; and TP-ST, 79.4 and 100%. The Strep A OIA is significantly more sensitive than TP-ST and compares favorably with culture.
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