These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Amyotrophic lateral sclerosis and intermittent self ventilation therapy. Indications and follow-up].
    Author: Buhr-Schinner H, Laier-Groeneveld G, Criée CP.
    Journal: Med Klin (Munich); 1995 Apr; 90(1 Suppl 1):49-51. PubMed ID: 7616923.
    Abstract:
    BACKGROUND: Fully informed patients were willing to start with IPPV. PATIENTS AND METHODS: Twenty-three patients with amyothropic lateral sclerosis (ALS) were treated with noninvasive intermittent mechanical ventilation (7 women, 16 men, mean age 59 years). The major symptoms were dyspnoe, heavy sleep disruption resulting in severely reduced quality of life. RESULTS: Their symptoms improved. The blood gases normalized during spontaneous breathing. They remained stable, despite a rapid decrease in respiratory force. Thirteen patients died, 6 during an acute event, 4 during bronchopulmonary infection and 3 stopped therapy, when they were fully ventilator dependent. CONCLUSION: We conclude that respiratory symptoms and quality of life can be improved by home intermittent mechanical ventilation. Indication should therefore be made earlier.
    [Abstract] [Full Text] [Related] [New Search]