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  • Title: Granulomatous interstitial nephritis associated with hydrochlorothiazide/amiloride.
    Author: Enríquez R, Cabezuelo JB, González C, Lacueva J, Teruel A, Fernández J, Arenas MD.
    Journal: Am J Nephrol; 1995; 15(3):270-3. PubMed ID: 7618655.
    Abstract:
    A 74-year-old woman developed acute renal failure and granulomatous interstitial nephritis associated with hydrochlorothiazide/amiloride. On stopping the drug the renal function improved, but not significantly. Around 20 months after prednisone administration, the renal function had stabilized, with a moderate degree of renal insufficiency. The case is discussed, and some aspects of acute interstitial nephritis induced by diuretics are briefly reviewed.
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