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  • Title: Menstrual cycle-related sensitivity to 35% CO2 in panic patients.
    Author: Perna G, Brambilla F, Arancio C, Bellodi L.
    Journal: Biol Psychiatry; 1995 Apr 15; 37(8):528-32. PubMed ID: 7619975.
    Abstract:
    In a double blind, random, cross-over design, 10 patients and seven controls inhaled one vital capacity of 35% CO2-65% O2 during their early-follicular and midluteal phases. Anxiety after CO2 intake was significantly stronger in the early-follicular phase than in the midluteal phase for patients. Controls had no anxiety reactions.
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